Figure 7.

(A-a) Schematic drawing of a two-step bioprinting strategy for design and fabrication of 3D pigmented human skin constructs, (A-b) fabrication process for the 3D pigmented human skin constructs, (B) representative images of 3D pigmented human skin constructs fabricated via 3D bioprinting. 3D bioprinted pigmented human skin constructs with uniform skin pigmentation, pigmented area is enclosed by the brown dotted line. scale bar: 2 mm, (C) representative images of H&E staining of 3D pigmented human skin constructs. scale bar: 50 μm. The epidermal region is indicated by E and the dermal region is indicated by D, and (D) representative images of Fontana Masson staining of 3D pigmented human skin constructs. scale bar: 50 μm. Arrows indicating the distribution of melanin granules within the epidermal region of 3D matrices (stained brownish-black).

Source: Adapted with permission from Ng et al. ¹⁸⁵