Figure 9.

Directed regeneration of sweat gland (SG) in thermal-injured mouse model after transplantation of induced SG cells (iSGCs): (a) schematic illustration of approaches for engineering iSGCs and transplantation, (b) sweat test of mice treated with different cells, (c) histology of plantar region without treatment and transplantation of MSCs and iSGCs (scale bars, 200 µm), (d) involvement of GFP-labeled iSGCs in directed regeneration of SG tissue in thermal-injured mouse model (K14, red; GFP, green; DAPI, blue; scale bar, 200 µm), and (e) SG-specific markers K14, K19, K8, and K18 detected in regenerated SG tissue (arrows) (K14, K19, K8, and K18, red; GFP, green; scale bars, 50 µm).

Source: Adapted with permission from Yao et al. ¹⁹⁶