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. 2021 Jul 2;8:666319. doi: 10.3389/fmed.2021.666319

Table 3.

Histologic characteristics of enrolled biopsies.

Variables PU <0.3 g/24 h (n= 40) PU ≥0.3 g/24 h (n= 125) P-value*
Score ≥1 n (%) Mean ± SD Score ≥1 n (%) Mean ± SD
i score 23 (57.5) 1.03 ± 1.07 65 (52) 0.87 ± 0.98 0.401
t score 11 (27.5) 0.43 ± 0.81 33 (26.4) 0.39 ± 0.74 0.811
v score 4 (10) 0.10 ± 0.30 7 (5.6) 0.08 ± 0.35 0.746
g score 22 (55) 0.83 ± 0.90 59 (47.2) 0.84 ± 1.01 0.933
ptc score 11 (27.5) 0.60 ± 1.06 47 (37.6) 0.70 ± 1.03 0.612
C4d 4 (10) 0.25 ± 0.78 29 (23.2) 0.45 ± 0.88 0.178
ci score 22 (55) 0.90 ± 0.98 75 (60) 0.89 ± 0.90 0.943
ct score 25 (62.5) 1.00 ± 0.99 75 (60) 0.89 ± 0.90 0.504
cv score 30 (75) 1.45 ± 1.11 97 (77.6) 1.55 ± 1.07 0.604
cg score** 25 (62.5) 1.95 ± 0.85 97 (77.6) 2.23 ± 0.79 0.056
ah score 37 (92.5) 2.48 ± 0.93 117 (93.6) 2.34 ± 0.89 0.424
mm score 21 (52.5) 0.70 ± 0.76 79 (63.2) 1.03 ± 0.98 0.052
*

P-values indicated group differences by Student's t-test for proteinuria <0.3 g/24 h compared with proteinuria ≥0.3 g/24 h.

**

Score ≥ 2 n (%).

i score, interstitial inflammation; t score, tubulitis; v score, intimal arteritis; g score, glomerulitis; ptc score, peritubular capillaritis; C4d, endothelial cells C4d staining extent of peritubular capillary and medullary vasa recta; ci score, interstitial fibrosis; ct score, tubular atrophy; cv score, vascular fibrous intimal thickening; cg, score, glomerular basement membrane double contours; ah score, arteriolar hyalinosis; mm score, mesangial matrix expansion.