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. 2021 Jul 2;9:685379. doi: 10.3389/fcell.2021.685379

FIGURE 1.

FIGURE 1

Identification of a prognosis-related ARG-based signature. (A) Nineteen overlapping prognostic ARGs based on TCGA and GSE31210. (B) Selection of the optimal parameter (lambda) in the least absolute shrinkage and selection operator (LASSO) model; dotted vertical lines were drawn at the optimal values using the minimum criteria. (C) LASSO coefficient profiles of the 19 prognosis-associated ARGs with non-zero coefficients determined by the optimal lambda. (D) Multivariate Cox regression analysis screened six ARGs (APOC3, EPOR, H2AFX, MXD1, PLCG2, and YWHAZ) to construct a risk signature. *P < 0.05 and **P < 0.01.