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. 2021 Jul 2;9:685379. doi: 10.3389/fcell.2021.685379

TABLE 1.

Prognostic roles of the ARGs signature with different demographic and clinical characteristics in TCGA training set (OS).

Characteristics Number (high-/low-risk group) % HR (95% CI) P-value
Age (years)
≥65 130/141 55.3% 2.062 (1.357–3.132) 0.001
<65 115/104 44.7% 1.636 (0.995–2.690) 0.052
Sex
Female 122/144 54.3% 1.516 (0.978–2.349) 0.063
Male 123/101 45.7% 2.347 (1.435–3.839) 0.001
Stage
I 109/152 53.3% 1.329 (0.772–2.288) 0.306
II 69/48 23.9% 1.844 (0.994–3.422) 0.052
III 49/30 16.1% 2.290 (1.122–4.671) 0.023
IV 14/11 5.1% 1.450 (0.482–4.355) 0.508
NA 4/4 1.6%
T stage
T1 59/107 33.9% 1.420 (0.751–2.686) 0.280
T2 145/113 52.7% 1.866 (1.206–2.889) 0.005
T3 29/16 9.2% 5.638 (1.261–25.205) 0.024
T4 11/7 3.7% 1.274 (0.316–5.138) 0.733
NA 1/2 0.6%
M stage
M0 173/149 65.7% 1.847 (1.241–2.747) 0.002
M1 14/10 4.9% 1.699 (0.520–5.549) 0.380
NA 58/86 29.4%
N stage
N0 144/173 64.7% 1.622 (1.01902.583) 0.042
N1 53/39 18.8% 1.523 (0.834–2.781) 0.171
N2 43/25 13.9% 2.264 (1.063–4.825) 0.034
N3 1/1 0.4%
NA 4/7 2.2%

NA, not available; HR, hazard ratio; CI, confidence interval; OS, overall survival.