Table 1.
Peptide docking results.
| Ligand | Binding affinity (kcal/mol) | |||
|---|---|---|---|---|
| EGFR | PI3K | Akt1 | CDK4 | |
| Inhibitor (positive control) | -8.2 | -9 | -9.8 | -9 |
| WPPNYQW | -9.5 | -10.6 | -11.3 | -9.4 |
| YDWRF | -9.3 | -9.4 | -10.7 | -9.3 |
| EMEWR | -8.3 | -8.2 | -9.4 | -7.4 |
| EEELAALVLDNGSGMCK | -6.1 | -6.8 | -6.1 | -5.7 |
| KMLWK | -7.8 | -7.5 | -8.9 | -6.7 |
| MMSLHL | -6.8 | -7.9 | -8.5 | -7.1 |
| RMCCCSPLK | -7.2 | -6.9 | -7.6 | -5.3 |
| TEFHLL | -8.3 | -8.4 | -9.5 | -7.6 |
| VELWR | -8.5 | -8.3 | -8.9 | -8 |
| VMLGMLWTLLLR | -4.7 | -5.3 | -8.1 | -8 |
| WNWKL | -8.7 | -8.9 | -8 | -9.2 |
| WNWKV | -9.5 | -9 | -8.5 | -8.9 |
Abbreviations: Akt1, Protein Kinase B1; CDK4, Cyclin-Dependent Kinase 4; EGFR, Epidermal Growth Factor Receptor; PI3 K, Phosphatidylinositol-3 kinase.