HD induces T-ALL cell cycle arrest at the G2/M phase. (a) Both cells were treated with HD (0, 7.5, and 15 µM) for 48 h, followed by PI staining and flow cytometry analysis of cell cycle distribution. (b) Cell cycle distribution analysis of (a). HD vs. control, **p< 0.01, ***p< 0.001. (c) The expression levels of cell cycle-related proteins after treatment with HD (0, 7.5, and 15 µM) for 24 and 48 h, with β-tubulin as loading control.