TABLE 4.
Univariate analysis of baseline variables according to response to treatment.
| Variables | Responders (n = 20) | Nonresponders† (n = 31) | p value |
|---|---|---|---|
| Gender (M:F) | 14:6 | 14:17 | 0.082 |
| Assigned treatment; n (%) | — | — | 0.006 |
| Midodrine/octreotide | 5 (25) | 20 (64.52) | — |
| Norepinephrine | 15 (75) | 11 (35.48) | — |
| Age (year) | 58.60 ± 8.39 | 61.60 ± 6.98 | 0.143 |
| Serum bilirubin (mg/dl)* | 3.12 (8.10) | 3.0 (5.60) | 0.132 |
| Serum albumin (g/dl) | 2.38 ± 0.457 | 2.32 ± 0.454 | 0.961 |
| Child–Pugh score | 10.85 ± 2.007 | 12.11 ± 1.77 | 0.031 |
| Serum sodium (mEq/L) | 125.5 ± 7.93 | 128.7 ± 8.40 | 0.275 |
| Serum creatinine (mg/dl) | 2.925 ± 0.981 | 2.471 ± 0.670 | 0.06 |
| Blood urea nitrogen (mg/dl) | 149.4 ± 70.53 | 148.6 ± 53.89 | 0.893 |
| Urine output (ml/day) | 652.5 ± 454.9 | 563.2 ± 453.7 | 0.410 |
| MAP (mmHg) | 77.20 ± 7.585 | 77.89 ± 7.99 | 0.567 |
| SOFA score | 6.30 ± 2.17 | 7.785 ± 2.92 | 0.045 |
Data are mean ± SD; *Median (IQR); MAP, mean arterial pressure (mmHg); SOFA, sequential organ failure assessment score; n, number of patients. † Two patients were considered as partial responders (one patient in each study group)12.