Table 1.
Study Details
| Author (year) | Accrual year | Country | Study design | Total No. of cases (SP/CS) |
Pancreatic tumor, No. (%) | Tumor size, mm |
Age, yr | Male sex, No. (%) |
Needle size, G | Needle type | Suction, mL |
Definition of blood contamination | Definition of cellularity |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Iwashita et al. (2012)32 |
2011 | USA | Retrospective, abstract only | 60 (40/20) | 50 (83) | NA | 68* | 39 (65) | 25 | FNB | 10 | NA | Presence of visible core |
| Nakai et al. (2014)8 |
2011–2013 | Japan | Retrospective | 97 (44/53)‡ | 97 (100) | 25* | 68* | 51 (61) | 22, 25 | FNA | 10 | "2–3" of 0–3¶ | |
| Goong et al. (2015)28 |
NA | Korea | Prospective, abstract only | 56 (56/56)** | 56 (100) | NA | NA | NA | 22, 25 | FNB | NA | NA | Adequate tissue for histology |
| Kin et al. (2015)29 |
2013 | Japan | Prospective | 40 (40/40)** | 40 (100) | 38† | 68† | 18 (45) | 22 | FNA | 20 | NA | NA |
| Chen et al. (2016)33 |
2010–2015 | Korea | Retrospective | 102 (31/71) | 102 (100) | 34* | 53* | 67 (66) | 22 | FNA | 5, 10, 20 | "2–3" of 0–3¶ | |
| El Haddad et al. (2016)34 |
2012–2013 | France | Retrospective | 98 (47/51) | 98 (100) | 33.1† | 68† | 56 (57) | 22 | FNB | 10 | NA | "Good" of 3 groups |
| Yamakita et al. (2017)30 |
NA | Japan | Prospective, abstract only | 89 (89/89)** | 60 (67) | 28† | 69† | 47 (53) | NA | FNA | 20 | NA | NA |
| Bansal et al. (2017)21 |
2015 | India | RCT | 200 (100/100) | 36 (18) | NA | 52† | 129 (65) | 19, 22, 25 | FNA | 10 | "3" of 1–3¶ | |
| Weston et al. (2017)22 |
2012–2013 | USA | RCT | 60 (30/30) | 60 (100) | 31 (SP), 24 (CS)† |
65(SP), 61(CS)† | 35 (58) | 22 | FNB | 10 | NA | "2–3" of 0–3¶ |
| Wang et al. (2017)35 |
2013–2014 | China | Retrospective | 149 (34/115) | 69 (46) | NA | 54* | 95 (64) | 22 | FNA | 5, 10 | "Significant" of 3 groups¶ | "3–5" of 0–5¶ |
| Lee et al. (2018)23 |
2015–2016 | Korea | RCT | 48 (48/48)** | 48 (100) | 37.6† | 68† | 29 (60) | 22 | FNA | NA | "Moderate-high" of 3 groups¶ |
Adequate quantity for histology |
| Saxena et al. (2018)24 |
2013–2014 | USA | RCT | 121 (61/60) | 121 (100) | 32 (SP), 28 (CS)† |
64† | 70 (58) | 22 | FNA | 10 | NA | Presence of core |
| Yang et al. (2018)36 |
2015–2016 | Japan | Retrospective | 194 (NA)§ | 194 (100) | 28.89† | 68† | 121 (62) | 19, 22, 25 | FNA, FNB | NA | NA | NA |
| Bor et al. (2019)31 |
2014–2016 | Hungary | Prospective | 92 (92/92)||,** | 92 (100) | 31.8† | 66† | 38 (43) | 22 | FNA | 5 | NA | Presence of histological sample |
| Lee et al. (2019)25 |
2015–2016 | Korea | RCT | 50 (50/50)** | 50 (100) | NA | 67† | 27 (54) | 22 | FNB | 10 | "2–3" of 1–3¶ | |
| Cheng et al. (2020)26 |
2015–2016 | Brazil | RCT | 50 (50/50)** | 50 (100) | NA | 64† | 29 (58) | 22 | FNA | 10 | "3" of 0–3¶ | |
| Di Mitri et al. (2020)27 |
2017–2018 | Italy | RCT | 110 (55/55) | 110 (100) | 35.9 (SP), 37.6 (CS)† |
71† | 49 (45) | 20 | FNB | 10 | "Moderate-high" of 4 groups¶ |
NA |
SP, slow pull; CS, conventional suction; G, gauge; NA, not available; RCT, randomized controlled trial; FNB, fine-needle biopsy; FNA, fine-needle aspiration.
*Median; †Mean; ‡97 FNAs performed in 93 cases; §194 FNAs/Bs performed in 175 cases; ||92 FNAs performed in 89 cases; ¶Semiquantitative evaluation; **Crossover studies.