Table 2.
Laboratory data
| Patient 1 | Patient 2 | Patient 3 | Patient 4 | Patient 5 | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Variables | Normal Range | Base line | Day3 | Day6 | Day14 | Base line | Day3 | Day6 | Day14 | Base line | Day3 | Day6 | Day14 | Base line | Day3 | Day6 | Day14 | Base line | Day3 | Day6 | Day14 |
| Routine blood tests | |||||||||||||||||||||
| WBC count (× 109/L) | 3400–12,500 | 10940 | 14910 | 16710 | 14220 | 9600 | 7560 | 10620 | 8050 | 10400 | 11040 | 10950 | 11630 | 6100 | 12740 | 10050 | 9040 | 15106 | 14870 | 20850 | 24500 |
| Hb (g/L) |
M: 14–18 F: 12–16 |
12.1 | 12.7 | 15.1 | 13.7 | 11.5 | 11 | 11 | 13.5 | 13.1 | 14.2 | 13.5 | 15.1 | 14.7 | 15.1 | 14.4 | 13.8 | 13 | 13.4 | 14 | 9.3 |
| PLT count (× 109/L) | 150,000–450,000 | 146 | 195 | 227 | 218 | 233 | 321 | 428 | 295 | 287 | 243 | 192 | 205 | 307 | 328 | 183 | 189 | 423 | 501 | 534 | 269 |
| Neutrophil (%) | 45–75 | NA | 88 | 88 | 70 | 90 | 80 | 83 | 62 | 90 | 82 | 70 | 71 | 86 | 91 | 71 | 81 | 97 | 87 | 98 | 94 |
| Lymphocyte (%) | 20–40 | NA | 2 | 10 | 19 | 4 | 9 | 11 | 26 | 5 | 10 | 20 | 20 | 8 | 2 | 21 | 14 | 3 | 5 | 2 | 2 |
| LYM count (× 109/L) | 1.0–4.0 | NA | 298.2 | 1671 | 2701.8 | 384 | 680.4 | 1168.2 | 2093 | 520 | 1104 | 2190 | 2326 | 640 | 254.8 | 2110.5 | 1265.6 | 453.18 | 743.5 | 417 | 490 |
| ESR (mm/h) |
M: 0 to 20 F: 0 to 25 |
96 | 73 | 23 | 26 | 104 | NA | NA | 51 | 74 | 9 | 25 | 10 | 37 | 5 | 64 | 17 | 80 | 50 | NA | 61 |
| D-Dimer (ng/ml) | Up to 442 | 441 | 481 | 436 | 416 | 2071 | 1573 | 869 | 589 | 779 | 1234 | 11302 | 13321 | 15000> | 12540 | 13214 | 10222 | 11321 | 11206 | 10278 | 9278 |
| Myocardial enzymes | |||||||||||||||||||||
| CPK (U/L) | 5 to 25 | 21.5 | 38 | 10 | 16.8 | 16 | 3.23 | 7.7 | 17.6 | 61 | 249 | 38 | 22 | 104 | 125 | 34 | 34 | 128 | 232 | 119 | 65 |
| Troponin I (ng/ml) | ≤ 0.4 | 0.1 | 1.4 | 1.4 | 0.1 | 3.4 | 1.06 | 0.88 | 0.72 | 4.5 | 0.4 | 0.6 | 0.84 | 3.7 | 1.5 | 0.8 | 0.9 | 1.3 | 4.4 | 0.67 | 17.6 |
| LDH (U/L) | 240–480 | 723 | 939 | 462 | 374 | 860 | 483 | 427 | 545 | 542 | 465 | 392 | 398 | 1458 | 1117 | 615 | 417 | 987 | 1182 | 1628 | 906 |
| Biochemical indicators | |||||||||||||||||||||
| Total Bili (mg/dl) | 0.1–1.2 | 0.26 | 0.7 | 1 | 0.6 | 1.1 | 0.54 | 0.43 | 0.9 | 0.7 | 0.6 | 0.7 | 1.3 | 1.6 | 1.6 | 1.6 | 0.9 | 4.55 | 4.3 | 2.6 | 1.3 |
| Direct Bili (mg/dl) | Up to 0.3 | 0.1 | 0.3 | 0.3 | 0.1 | 0.3 | 0.2 | 0.02 | 0.1 | 0.1 | 0.1 | 0.2 | 0.2 | 1.2 | 0.6 | 0.3 | 0.2 | 0.41 | 0.8 | 0.6 | 0.3 |
| ALT (U/L) |
M: up to 41 F: up to 31 |
55 | 29 | 40 | 43 | 98 | 41 | 42 | 39 | 16 | 43 | 30 | 11 | 136 | 106 | 55 | 75 | 66 | 20 | 19 | 20 |
| AST (U/L) |
M: up to 38 F: up to 31 |
23.5 | 20 | 25 | 20 | 68 | 47.5 | 25 | 18 | 19 | 40 | 15 | 35 | 145 | 50 | 29 | 27 | 101 | 30 | 25 | 25 |
| BUN (mmol/L) | 7–20 | 6 | 23 | 24 | 16 | 23 | 54 | 43 | 21 | 25.2 | 16 | 21 | 21 | 25 | 14 | 11 | 11 | 18 | 20 | 20 | 25 |
| Cr (μmol/L) |
M: 0.7–1.4 F: 0.6–1.3 |
0.8 | 0.8 | 0.7 | 0.8 | 0.5 | 0.9 | 1 | 1.1 | 0.9 | 0.8 | 1.1 | 0.9 | 0.8 | 0.7 | 0.8 | 0.7 | 1.03 | 0.9 | 0.9 | 1.1 |
| K (mmol/L) | 3.6–5.2 | 4.1 | 4.8 | 4.8 | NA | 4.1 | 3.7 | 4.4 | 4.1 | 4.7 | 4.4 | 4.5 | 4.9 | 4.8 | 4.1 | 4.5 | 4.5 | 4.7 | 4.2 | 4.6 | 4.9 |
| Na (mEq/L) | 135–145 | 139 | 137 | 138 | NA | 144 | 143 | 139 | 145 | 144 | 142 | 141 | 145 | 144 | 137 | 142 | 145 | 141 | 136 | 139 | 138 |
| Inflammatory markers | |||||||||||||||||||||
| CRP (mg/L) | Up to 10 | 60.5 | 6 | 3 | 0.48 | 107 | 101 | 20 | 3.84 | 87 | 53.5 | 24.5 | 4.44 | 45 | 82 | 35 | 1.47 | 60 | 29.5 | 72.5 | 49 |
| Procalcitonin (ng/ml) | < 0.10 | 0.17 | 0.01 | 0.03 | 0.08 | 0.02 | 0.12 | 0.07 | 0.03 | 0.11 | 0.09 | 0.07 | 0.05 | 0.1 | 0.11 | 0.13 | 0.02 | 0.04 | 0.33 | 0.1 | 0.18 |
| Ferritin (ng/ml) |
M: 24 to 336 F: 11 to 307 |
1979 | 959 | 231 | 169 | 798 | 986 | 686 | 659 | 896 | 707 | 600 | 500 | 1087 | 2666 | 742 | 878 | 2314 | 1181 | 656 | 828 |