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. 2021 Jul 2;15:660942. doi: 10.3389/fnins.2021.660942

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Copyright © 2021 Manfready, Engen, Verhagen Metman, Sanzo, Goetz, Hall, Forsyth, Raeisi, Voigt and Keshavarzian.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Preprandial GLP-1 levels did not differ between PD and control subjects and did not correlate with PD clinical characteristics. (A) Fasting GLP-1 levels were statistically indistinguishable between control and PD subjects (p = 0.43). There was no relationship between GLP-1 and clinical characteristics including: (B) finger tapping (p = 0.98, r = 0.005, r² < 0.001), (C) MDS-UPDRS (p = 0.97, r = 0.01, r² < 0.001), and (D) disease duration (p = 0.27, r = 0.27, r² = 0.07).