Table 3.
Interval from exposure to diagnosis and treatments of five patients with acute thallium poisoning
Patient No. | Interval from exposure to diagnosis (d) |
Time of receiving treatments after exposure
|
Duration of PB treatment (d) |
Urine thallium concentration (µg/L)
|
Blood thallium concentration (µg/L)
|
|||||
Sodium thiosulfate
|
DMPS
|
HP
|
PB
|
Before treatment
|
After treatment
|
Before treatment
|
After treatment
|
|||
1 | 9 | 3rd day | 12th day | 15th day | 15th day | 14 | 7200 | 160 | 280 | 0 |
2 | 8 | 3rd day | 10th day | 10th day | 11th day | 15 | 5100 | 130 | 210 | 0 |
3 | 11 | 10th day | 11th day | 15th day | 15th day | 15 | 250 | 0 | 150 | 0 |
4 | 12 | 11th day | 11th day | 15th day | 15th day | 14 | 370 | 0 | 40 | 0 |
5 | 12 | 11th day | 11th day | 15th day | 15th day | 16 | 580 | 0 | 46 | 0 |
The urine and blood samples were successively sent to Hospital 307 of Chinese People’s Liberation Army to confirm the diagnosis of acute thallium poisoning. The day when the patients underwent detoxification treatments after exposure is listed in the table. The Prussian blue (PB) treatment was implemented in Hospital 307 of Chinese People’s Liberation Army and lasted for 14 to 16 d. The urine and blood thallium concentration before and after PB treatment was recorded. Sodium thiosulfate: 0.64 g, intravenous injection per day; DMPS: Dimercaptopropane sulfonate 0.25 g, intramuscular injection twice daily; HP: Hemoperfusion; PB: Prussian blue 3.3 g in mannitol 50 mL, orally four times daily.