Tab. I.
Summary of virological and epidemiological characteristics of SARS-CoV and SARS-CoV-2 infections.
| Characteristics | SARS-CoV | SARS-CoV-2 |
|---|---|---|
| First occurrence | Nov. 16, 2002 in Foshan, Guangdong | Dec. 07, 2019 in Wuhan, Hubei |
| Global alert declaration (WHO) | March 13, 2003 | Jan 30, 2020 |
| Pandemic declaration (WHO) | - | March 11th, 2020 |
| Genome | RNA | RNA |
| Length, bp | 29,751 | 29,811 |
| Mutation rate RNA | 0.80-2.38 × 10-3 subs/site/year | 7.8 × 10-4 subs/site/year |
| Moderate | High | |
| Mode of transmission | Respiratory droplet | Respiratory droplet |
| Contact | Contact | |
| - | Fecal-oral (?) | |
| - | Airborne (?) | |
| Incubation period (median) | 4.0 days (95% CI: 3.6-4.4) | 5.1 days (95% CI: 4.5-5.8) |
| R0 | 2-4 | 1.4-7.23 |
| Asymptomatic rate | 2.3-13% | 5-8% |
| Case fatality rate | 9.6% | 5.1% |
SARS-CoV: severe acute respiratory syndrome; SARS-CoV-2: coronavirus disease-2019; bp: base pairs; R0: basic reproduction number; CI: confidence interval.