Table 3. Performance of TVUS ET Thresholds for Identifying Endometrial Cancer Among a Simulated Cohort of US Black and White Women With Postmenopausal Bleeding.
| Threshold, mm | % (95% CI) | AUC (95% CI) | |||
|---|---|---|---|---|---|
| Sensitivity | Specificity | PPV | NPV | ||
| Black women | |||||
| ≥3 | 51.1 (49.6-52.6) | 55.0 (54.5-55.5) | 11.2 (10.8-11.6) | 91.0 (90.6-91.4) | 0.57 (0.56-0.57) |
| ≥4 | 47.5 (46.0-49.0) | 64.9 (64.4-65.3) | 13.1 (12.5-13.6) | 91.7 (91.4-92.1) | |
| ≥5 | 43.7 (42.3-45.2) | 74.1 (73.7-74.5) | 16 (15.2-16.5) | 92.2 (91.9-92.5) | |
| White women | |||||
| ≥3 | 89.5 (89.1-89.8) | 25.7 (25.6-25.9) | 11.8 (11.7-11.9) | 95.6 (95.5-95.8) | 0.73 (0.73-0.74) |
| ≥4 | 87.9 (87.6-88.3) | 42.7 (42.5-42.9) | 14.6 (14.4-14.7) | 97.0 (96.9-97.0) | |
| ≥5 | 86.0 (85.6-86.4) | 58.5 (58.3-58.7) | 18.7 (18.5-18.9) | 97.4 (97.3-97.5) | |
Abbreviations: AUC, area under the curve; ET, endometrial thickness; NPV, negative predictive value; PPV, positive predictive value; TVUS, transvaginal ultrasound.