Skip to main content
. 2021 Feb 26;42(7):940–950. doi: 10.1093/carcin/bgab017

Figure 1.

Figure 1.

Luteolin inhibits pancreatic carcinogenesis and cell proliferation in a hamster model. Body-weights (A) and representative histology of hamster PDAC in controls; on the left, a low power field (×20), on the right, a high power field (×100) (B). The incidence in all lobes (C) and multiplicity in all, duodenal, splenic, and gastric lobes (D). The proportion of normal, PanIN1, PanIN2, PanIN3 and PDAC in all pancreatic ducts (diameter > 200 mm) of duodenal lobes (E) and the progression score calculated by weighting respective lesions (normal = 0, PanIN1 = 1, PanIN2 = 2, PanIN3 = 3, PDAC = 4) (F), Immunohistochemical findings of Ki-67 (G) and Ki-67 labeling index in PanINs (H). Data represented as mean ± SD, n = 14 (Control) and 13 (Lut 100 ppm, Hes 100 ppm, 1000 ppm). *P < 0.05 statistically significant compared with controls.