FIGURE 3.

(A) Schematic illustration of the synthesis of AA@ICG@PLL gold (Au)-based nanoparticles (NPs). (B) Experimental design for tracking AA@ICG@PLL-labeled MSCs in a silica-induced PF mouse model. (C) Intracellular Au content measured by ICP-MS. (D) Relative viability of BMSCs labeled with AA@ICG@PLL NPs at various Au concentrations. (E) In vivo computed tomography (CT) images of AA@ICG@PLL-labeled BMSCs at 7, 14, and 21 days after transplantation. (F) Bright-field images of Oil Red O staining and ALP staining of NP-loaded and unloaded BMSCs. Scale bar = 20 mm (adapted by Huang et al., 2020). ^∗p < 0.05 compared with the unlabeled group.