A) NPRs of selected ligand containing RNA structures. PBD codes in red are helixes, PDB codes in blue are quadruplexes, PDB codes in magenta are riboswitches, and black PDB codes are other structures. B) NPRs of 300 liganded RNA structures. White points are negative DLID values, blue points are positive DLID values, and the size of the data point represents the magnitude of the DLID score. C) NPRs of 1000 representative protein structures from the PDB.