Table 1.

Properties of protein²⁶ and RNA structures from the PDB.

	Liganded Proteins (n = 46,221)		Liganded RNAs (n = 300)
	Average	Median	Average	Median
Volume (Å)	460 ± 360	350	450 ± 400	280
Buriedness	0.81 ± 0.09	0.81	0.78 ± 0.09	0.77
Hydrophobicity	0.53 ± 0.12	0.52	0.42 ± 0.10	0.41
DLID	−0.045 ± 0.81	0.13	−0.38 ± 0.72	−0.27
	All Proteins (n = 291,758)		All RNAs (n = 1552)
	Average	Median	Average	Median
Volume (Å)	270 ± 250	180	290 ± 330	190
Buriedness	0.76 ± 0.08	0.75	0.72 ± 0.08	0.72
Hydrophobicity	0.50 ± 0.11	0.49	0.35 ± 0.10	0.35
DLID	−0.70 ± 0.80	−0.84	−1.09 ± 0.77	−1.10