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. 2021 Jul 16;21:818. doi: 10.1186/s12885-021-08549-2

Table 4.

Univariable and multivariable analysis for overall survival (OS)

Variables Univariable analysis Multivariable analysis
HR (95% CI) P value HR (95% CI) P value
Treatment regimen
 mFOLFIRINOX vs Gemox 0.595 (0.312–1.135) 0.099 0.547 (0.264–1.131) 0.103
Age
 >58 vs ≤58 1.089 (0.567–2.092) 0.798
Sex
 male vs female 0.896 (0.650–1.235) 0.504
ECOG
 1 vs 0 1.709 (0.883–3.310) 0.112 2.148 (1.028–4.488) 0.042
Primary tumor sites
 Intrahepatic Ref
 Hilar 1.609 (0.827–3.129) 0.161 2.123 (1.023–4.402) 0.043
 Distal 0.893 (0.207–3.846) 0.879 0.890 (0.199–3.983) 0.878
Disease status
 Metastasis vs Locally advanced 0.939 (0.660–1.335) 0.724
Liver metastasis 1.393 (0.716–2.710) 0.329
CA19–9
 >40 vs ≤40 3.198 (1.237–8.266) 0.016 4.972 (1.768–13.980) 0.002

Bold values are statistically significant (p ≤ 0.05)

Ref reference, HR hazard ratio, CI confidence interval, ECOG Eastern Cooperative Oncology Group