Table 4.

Threshold effect analysis of DI on adverse clinical outcomes using piece-wise linear regression

DI	Crude		aAdjust
	LogRR(95%CI)	P value	LogRR(95%CI)	P value
< 1.1	0.6 (0.1, 2.9)	0.559	0.7 (0.1, 3.2)	0.597
≥1.1, < 1.2	0.0 (0.0, 1.7)	0.077	0.0 (0.0, 0.8)	0.041
≥1.2	2.8 (0.5, 15.3)	0.236	8.8 (1.4, 56.0)	0.021

Crude:none adjustment

^aAdjusted: gender; age; race; chemotherapy protocol; WBC; CNS Status; fusion gene; prednisone response; BM blasts on Day+ 29; immunophenotype; karyotype