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. 2021 Jul 1;11:638619. doi: 10.3389/fonc.2021.638619

Table 3.

Multivariate analysis of factors associated with post-recurrence survival in breast cancer patients.

Clinico-pathologic Characteristics HR 95%CI P value
Breast surgery 0.289
 Mastectomy 1.00
 BCS 0.39 0.07 - 2.23
Axillary surgery 0.625
 ALND 1.00
 SLNB 0.51 0.19 - 2.01 0.333
 None 0.00 0 - +∞ 0.978
pT 0.195
 3-4 1.00
 1-2 0.38 0.12 - 1.17 0.091
 is 0.26 0.04 - 1.58 0.142
ER status 0.014
 Positive 1.00
 Negative 2.30 1.18 - 4.48
Recurrent site 0.001
 LRR 1.00
 Viscera 6.69 2.50 - 17.87 <0.001
 Bone or soft tissues 4.52 1.57 - 13.04 0.005
ER conversion 0.375
 Remain negative 1.00
 Discordant 1.00 0.11 - 9.47 1.000
 Remain positive 0.41 0.03 - 5.27 0.496
PR conversion 0.934
 Remain negative 1.00
 Discordant 0.82 0.29 - 2.36 0.714
 Remain positive 0.00 0 - +∞ 0.956
DFI 0.792
 <2years 1.00
 ≥2years 1.12 0.49 - 2.57

OR, odds ratio; CI, confidence interval; BCS, breast-conserving surgery; ALND, axillary lymph node dissection; SLNB, sentinel lymph node biopsy; is, in situs; ER, estrogen receptor; LRR, loco-regional recurrence; pT, pathological tumor size stage; is, in situs; PR, progesterone receptor; DFI, disease-free interval.

The bold values mean the difference is statistically significant.