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. Author manuscript; available in PMC: 2021 Jul 16.
Published in final edited form as: Pediatr Blood Cancer. 2021 Mar 11;68(7):e28940. doi: 10.1002/pbc.28940

TABLE 3.

Comparisons of induction mortality by age category

Total N <1 year 1–10 years Crude HR
(95% CI)
p-Value Adjusted Model 1a
HR (95% CI)
p-Value Adjusted Model 2b
HR (95% CI)
p-Value
ALL 10 359 11 (2.7) 46 (0.5) 5.35 (2.76, 10.4) <.001 3.66 (1.69, 7.93) .001 2.15 (1.00, 4.81) .064
AML 871 6 (3.2) 14 (2.1) 1.56 (0.59, 4.13) .400 1.47 (0.64, 4.74) .274 1.29 (0.38, 4.41) .685

Abbreviations: ALL, acute lymphoid leukemia; AML, acute myeloid leukemia.

a

ALL model comparing <1 year versus 1–10-year age groups adjusted for race, ethnicity, and anthracycline exposure; AML model adjusted for race and ethnicity.

b

ALL model comparing <1 year versus 1–10-year age groups adjusted for race, ethnicity, anthracycline exposure, and acuity at presentation; AML model adjusted for race, ethnicity, and acuity at presentation.