TABLE 5.
Comparisons of the rate of utilization (use per 100 days) among users of specific resources during induction
| ALL | AML | Infant ALL vs. Infant AML Adjustedc RR (95% CI) |
|||||
|---|---|---|---|---|---|---|---|
| <1 year | 1–10 years | Adjusteda RR (95% CI) |
<1 year | 1–10 years | Adjustedb RR (95% CI) |
||
| Complete blood count | 85.9 | 87.5 | 0.98 (0.95, 1.02) | 92.5 | 93.5 | 0.99 (0.97, 1.01) | 1.01 (0.99, 1.04) |
| Blood culture | 21.0 | 22.8 | 0.92 (0.82, 1.04) | 8.3 | 10.6 | 0.79 (0.53, 1.17) | 2.59 (1.65, 4.05) |
| Antibiotics | 118.7 | 121.8 | 0.98 (0.93, 1.04) | 138.4 | 135.9 | 1.02 (0.96, 1.09) | 0.71 (0.66, 0.78) |
| Antifungals | 72.7 | 54.4 | 1.34 (1.22, 1.46) | 81.9 | 80.2 | 1.02 (0.97, 1.08) | 0.87 (0.78, 0.97) |
| Antivirals | 23.4 | 32.8 | 0.71 (0.50, 1.02) | 35.8 | 32.9 | 1.12 (0.67, 1.88) | 0.74 (0.42, 1.32) |
| Total blood products | 29.5 | 25.2 | 1.17 (1.05, 1.29) | 46.9 | 45.2 | 1.04 (0.94, 1.15) | 0.75 (0.66, 0.84) |
| GCSF | 53.7 | 26.7 | 2.01 (1.75, 2.31) | 31.2 | 29.8 | 1.05 (0.74, 1.48) | 0.72 (0.46, 1.13) |
| Non-opioid analgesics | 22.9 | 24.7 | 0.93 (0.83, 1.03) | 27.9 | 32.3 | 0.86 (0.76, 0.98) | 0.92 (0.81, 1.04) |
| Opioid analgesics | 35.5 | 34.2 | 1.04 (0.97, 1.11) | 40.8 | 35.6 | 1.15 (0.99, 1.33) | 0.90 (0.77, 1.05) |
| Antiemetics | 39.1 | 22.6 | 1.73 (1.58, 1.89) | 56.8 | 52.2 | 1.09 (0.98, 1.17) | 0.87 (0.79, 0.95) |
| Total parenteral nutrition | 37.3 | 33.2 | 1.12 (0.97, 1.30) | 43.8 | 44.8 | 0.98 (0.84, 1.14) | 0.78 (0.63, 0.95) |
| Antihypertensives | 32.0 | 33.0 | 0.97 (0.82, 1.14) | 11.0 | 12.0 | 0.91 (0.39, 2.14) | 2.05 (1.01, 4.11) |
| Diuretics | 15.5 | 17.3 | 0.90 (0.78, 1.03) | 26.9 | 22.3 | 1.21 (0.94, 1.55) | 0.56 (0.42, 0.74) |
| Vasopressors | 5.1 | 5.9 | 0.87 (0.49, 1.53) | 14.4 | 15.3 | 0.94 (0.52, 1.69) | 0.72 (0.46, 1.13) |
| Supplemental oxygen | 7.4 | 5.7 | 1.31 (0.87, 1.96) | 18.9 | 15.8 | 1.20 (0.92, 1.58) | 0.78 (0.60, 1.02) |
| Ventilation | 15.1 | 21.9 | 0.69 (0.56, 0.85) | 28.1 | 37.8 | 0.74 (0.53, 1.04) | 0.61 (0.42, 0.88) |
| ECMO | 22.9 | 23.1 | 0.99 (0.29, 3.36) | 39.30 | 32.50 | 1.59 (0.62, 4.09) | 0.36 (0.12, 1.12) |
| Dialysis | 8.40 | 15.90 | 0.56 (0.26, 1.22) | 24.20 | 25.60 | 0.94 (0.22, 4.13) | 0.58 (0.23, 1.48) |
Abbreviations: ALL, acute lymphoid leukemia; AML, acute myeloid leukemia; ECMO, extracorporeal membrane oxygenation; GCSF, granulocyte colony-stimulating factor.
a
Rate ratio comparing resource use among infants with ALL versus noninfants aged 1–10 years with ALL; adjusted for race, ethnicity, and acuity at presentation.
b
Rate ratio comparing resource use among infants with AML versus noninfants aged 1–10 years with AML; adjusted for race, ethnicity, and acuity at presentation.
c
Rate ratio comparing resource use among infants with ALL versus infants with AML; adjusted for race, ethnicity, and acuity at presentation.