Table 5.

Perceived benefits and challenges regarding the current individualized (X) DR TB treatment

		Indonesia	Kyrgyzstan	Nigeria
Acceptability	Perceived benefits regarding the current ITR	• Proven efficacy according to WHO • Monitoring and management of AEs covered by health insurance • Enablers and nutrition provided with the regimen	• Reduced side effects of current ITR compared to the one before • Good completion rates • No resistance yet	• Use in children possible • Funding for drugs through the Global Fund • Monitoring also funded
	Perceived challenges regarding the current ITR	• Long duration of treatment • High pill burden • High health worker and health facility workload • Side effects common • Injectables
		• Difficulty in quantification and forecasting due to individual dosing	• Limited adherence • Difficulties with treatment monitoring • Difficulties in allocating treatment in children	• Injectables (resulting in AEs and high HR needs) • Hospitalization • High workload on home visits if home-based care setting • Diagnostic treatment gap due to lack of funding for travel for baseline investigations • Limited adherence • Lack of tests for all examinations for AEs • High cost for monitoring • Difficulty in quantification and forecasting due to individual dosing

AE adverse event, ITR individualized treatment regimen, HR human resources