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. 2021 Jul 15;28(1):1510–1523. doi: 10.1080/10717544.2021.1951894

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© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 8. — Antitumor activity in vivo. Mice (n = 6) were given 19 days of oral administration of DTX, EXO, and EXO-DTX. (A) After anesthesia, tumor tissues were resected from mice for imaging purposes. (B) Tumor tissues were monitored at an interval of two days. ***p< 0.001 compared to control, ^###p< 0.001compared to the DTX group. (C) Tumor weight. ***p< 0.001 compared to control, ^###p< 0.001 compared to the DTX group. (D) The body weight. Values were displayed as mean ± SD. **p< 0.01, ***p< 0.001 compared to control, ^##p< 0.01, ^###p< 0.001 compared to the DTX group (4 mg/kg).