Table 2.
Variables | Day | Silymarin | Placebo | P-value |
---|---|---|---|---|
AST (U/l) | Baseline | 215.14 ±91.61 | 201.88 ±65.78 | 0.43 |
Day 3 | 180.42 ±85.22 | 197.48 ±58.31 | 0.27 | |
Day 7 | 144.24 ±73.37 | 184.93 ±57.02 | 0.04 | |
Day 9 | 111.33 ±61.43 | 161.37 ±55.01 | < 0.001 | |
Day 14 | 79.26 ±49.95 | 133.97 ±52.94 | < 0.001 | |
ALT (U/l) | Baseline | 181.84 ±81.59 | 178.22 ±65.78 | 0.81 |
Day 3 | 149.15 ±74.19 | 176.04 ±55.50 | 0.055 | |
Day 7 | 116.55 ±63.39 | 164.82 ±55.19 | 0.062 | |
Day 9 | 84.86 ±52.28 | 138.73 ±53.63 | < 0.001 | |
Day 14 | 58.75 ±42.10 | 112.75 ±51.39 | < 0.001 | |
ALP (U/l) | Baseline | 272.15 ±44.06 | 268.05 ±54.11 | 0.79 |
Day 3 | 254.15 ±42.09 | 258.70 ±50.77 | 0.75 | |
Day 7 | 222.40 ±39.19 | 252.30 ±49.68 | 0.041 | |
Day 9 | 197.60 ±39.42 | 229.07 ±50.80 | 0.027 | |
Day 14 | 154.80 ±40.11 | 209.45 ±49.69 | < 0.001 |
AST – aspartate aminotransferase, ALT – alanine transaminase, ALP – alkaline phosphatase