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. 2021 Jun 22;7(2):149–155. doi: 10.5114/ceh.2021.107067

Table 2.

Comparison between mean aspartate aminotransferase, alanine aminotransferase, and alkaline phosphatase on different days in silymarin and placebo groups

Variables Day Silymarin Placebo P-value
AST (U/l) Baseline 215.14 ±91.61 201.88 ±65.78 0.43
Day 3 180.42 ±85.22 197.48 ±58.31 0.27
Day 7 144.24 ±73.37 184.93 ±57.02 0.04
Day 9 111.33 ±61.43 161.37 ±55.01 < 0.001
Day 14 79.26 ±49.95 133.97 ±52.94 < 0.001
ALT (U/l) Baseline 181.84 ±81.59 178.22 ±65.78 0.81
Day 3 149.15 ±74.19 176.04 ±55.50 0.055
Day 7 116.55 ±63.39 164.82 ±55.19 0.062
Day 9 84.86 ±52.28 138.73 ±53.63 < 0.001
Day 14 58.75 ±42.10 112.75 ±51.39 < 0.001
ALP (U/l) Baseline 272.15 ±44.06 268.05 ±54.11 0.79
Day 3 254.15 ±42.09 258.70 ±50.77 0.75
Day 7 222.40 ±39.19 252.30 ±49.68 0.041
Day 9 197.60 ±39.42 229.07 ±50.80 0.027
Day 14 154.80 ±40.11 209.45 ±49.69 < 0.001

AST – aspartate aminotransferase, ALT – alanine transaminase, ALP – alkaline phosphatase