Table 4.
HLA | Healthy controls (n= 50) (57 alleles) | AIH1 (n= 14) (35 alleles) | Odd ratio | p-value | AIH2 (n= 5) (16 alleles) | Odd ratio | p-value |
---|---|---|---|---|---|---|---|
DRB1* | |||||||
DRB1*01 | 2 (3.5%) | 2 (5.7%) | 1.6 (0.3-11.7) | 0.2 | 0 | 0 | |
DRB1*03 | 3 (5.2%) | 5 (14.2%) | 3.8 (1.7-8.6) | 0.01 | 1 (6.2%) | 3.1 (0.4-22.1) | 0.3 |
DRB1*04 | 6 (10.5%) | 6 (17.1%) | 3.2 (1.3-7.6) | 0.01 | 0 | 0 | |
DRB1*07 | 7 (12.2%) | 4 (11.4%) | 1.9 (0.7-5) | 0.1 | 5 (31.2%) | 0 | |
DRB1*09 | 2 (3.5%) | 2 (5.7%) | 2.5 (0.8-7.5) | 0.2 | 0 | 0 | |
DRB1*10 | 3 (5.2%) | 1 (2.8%) | 1.1 (0.1-6.7) | 0.6 | 1 (6.2%) | 3.1 (0.4-22.1) | 0.3 |
DRB1*11 | 12 (21%) | 3 (8.5%) | 0.8 (0.2-2.7) | 0.5 | 3 (18.7%) | 4 (0.7-21) | 0.1 |
DRB1*13 | 5 (8.7%) | 7 (20%) | 4.3 (1.8-10) | 0.002 | 4 (25%) | 20.4 (2.5-166) | 0.002 |
DRB1*14 | 3 (5.2%) | 2 (5.7%) | 1.9 (0.6-6.4) | 0.2 | 1 (6.2%) | 3.1 (0.4-22.1) | 0.3 |
DRB1*15 | 12 (21%) | 1 (2.8%) | 0.4 (0.07-3.7) | 0.3 | 1 (6.2%) | 1.2 (0.1-10) | 0.6 |
DRB1*16 | 2 (3.5%) | 2 (5.7%) | 1.6 (0.4-55) | 0.3 | 0 | 0 | |
DRB3*/4*/5* | |||||||
DRB3 | 13 (22.8%) | 12 (34.2%) | 9.3 (2.2-38) | 0.0001 | 5 (31.2%) | 0 | |
DRB4 | 8 (14%) | 10 (28.5%) | 6.3 (2.2-17) | 0.0001 | 3 (18.7%) | 6 (1.1-31) | 0.04 |
DRB5 | 5 (8.7%) | 4 (11.4%) | 2.4 (0.9-6.1) | 0.09 | 4 (25%) | 20 (2.5-162) | 0.002 |
Values of p < 0.05 (significant) are shown in bold font.