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. 2021 Jun 30;7(2):178–182. doi: 10.5114/ceh.2021.106865

Table 4.

Allele frequencies among Iraqi children AIH type 1, AIH type 2 and healthy controls

HLA Healthy controls (n= 50) (57 alleles) AIH1 (n= 14) (35 alleles) Odd ratio p-value AIH2 (n= 5) (16 alleles) Odd ratio p-value
DRB1*
DRB1*01 2 (3.5%) 2 (5.7%) 1.6 (0.3-11.7) 0.2 0 0
DRB1*03 3 (5.2%) 5 (14.2%) 3.8 (1.7-8.6) 0.01 1 (6.2%) 3.1 (0.4-22.1) 0.3
DRB1*04 6 (10.5%) 6 (17.1%) 3.2 (1.3-7.6) 0.01 0 0
DRB1*07 7 (12.2%) 4 (11.4%) 1.9 (0.7-5) 0.1 5 (31.2%) 0
DRB1*09 2 (3.5%) 2 (5.7%) 2.5 (0.8-7.5) 0.2 0 0
DRB1*10 3 (5.2%) 1 (2.8%) 1.1 (0.1-6.7) 0.6 1 (6.2%) 3.1 (0.4-22.1) 0.3
DRB1*11 12 (21%) 3 (8.5%) 0.8 (0.2-2.7) 0.5 3 (18.7%) 4 (0.7-21) 0.1
DRB1*13 5 (8.7%) 7 (20%) 4.3 (1.8-10) 0.002 4 (25%) 20.4 (2.5-166) 0.002
DRB1*14 3 (5.2%) 2 (5.7%) 1.9 (0.6-6.4) 0.2 1 (6.2%) 3.1 (0.4-22.1) 0.3
DRB1*15 12 (21%) 1 (2.8%) 0.4 (0.07-3.7) 0.3 1 (6.2%) 1.2 (0.1-10) 0.6
DRB1*16 2 (3.5%) 2 (5.7%) 1.6 (0.4-55) 0.3 0 0
DRB3*/4*/5*
DRB3 13 (22.8%) 12 (34.2%) 9.3 (2.2-38) 0.0001 5 (31.2%) 0
DRB4 8 (14%) 10 (28.5%) 6.3 (2.2-17) 0.0001 3 (18.7%) 6 (1.1-31) 0.04
DRB5 5 (8.7%) 4 (11.4%) 2.4 (0.9-6.1) 0.09 4 (25%) 20 (2.5-162) 0.002

Values of p < 0.05 (significant) are shown in bold font.