Figure 1.

Expression of ephrinAs/EphA mRNA in the mouse retina and Müller cells.

(A) Relative expression of ephrin-A2 (A2), ephrin-A3 (A3) and their receptor EphA4 mRNA in adult retina (white bar) and purified mouse Müller cells (black bar). Note ephrin-A2/A3 and EphA4 are enriched in Müller cells. Statistical analysis was performed by unpaired t-test. *P < 0.05, vs. the corresponding mRNA expression in retina. (B) Relative expression of ephrin-A2/A3 and EphA4 mRNA in Müller cells derived from postnatal retinas and their expressions were normalized to that from postnatal day 5 (P5) Müller cells (MC). *P < 0.05, vs. the corresponding mRNA expression in P5 Müller cells. Statistical analysis was performed by one-way analysis of variance followed by Tukey’s post hoc test. Note ephrin-A2/A3 and EphA4 are highly expressed with maturation of Müller cells. n = 6 animals. Data are expressed as the mean ± SD.