Table 3.
Changes in motor function among the three groups after MIRT
| Items | PIGD group (n = 36) | TH group (n = 19) | Indeterminate group (n = 14) | |||
|---|---|---|---|---|---|---|
| Pre-MIRT | Post-MIRT | Pre-MIRT | Post-MIRT | Pre-MIRT | Post-MIRT | |
| MDS-UPDRS IIIa | 29.1±11.2 | 23.5±11.7** | 28.1±10.7 | 24.6±9.3** | 30.1±10.0 | 25.8±8.8** |
| Axial subscoresb (scores) | 5(3) | 4(2)** | 3(2) | 3(2)** | 5(1) | 4(1)* |
| Bradykinesia subscoresb | 13.5(9) | 12(8)** | 12(9) | 10(7)** | 12(6) | 10(8)** |
| Tremor subscoresb | 0(3) | 0(3) | 7(6) | 7(3) | 5(5) | 4(3)** |
| Rigidity subscoresb | 7(6) | 6(6)** | 6(3) | 5(5) | 5(5) | 5(4) |
| M-PASb | 50(9) | 53(8)** | 54(5) | 56(3) | 52(10) | 54(5)* |
| BBSb | 53(4) | 54(4)** | 55(3) | 55(4)** | 55(2) | 56(3)* |
| 10MT-Comfortable gait speeda (m/s) | 1.09±0.17 | 1.21±0.21** | 1.19±0.17 | 1.30±0.16** | 1.13±0.14 | 1.25±0.15** |
| 10MT-Fast gait speeda (m/s) | 1.44±0.23 | 1.54±0.23** | 1.48±0.22 | 1.64±0.24** | 1.52±0.22 | 1.65±0.22** |
| FTSTSb (s) | 11.2(3.4) | 10.0(3.5)** | 10.6(3.2) | 9.1(3.5)** | 9.0(2.2) | 7.7(1.6)** |
| 6MWDb (m) | 463(111) | 490(93)** | 466(137) | 516(88)** | 473.5(139) | 524(81)** |
| TUGb (s) | 9.9(2.3) | 8.7(2.0)** | 9.3(2.6) | 8.4(1.5)** | 9.2(3.2) | 7.9(1.5)** |
The paired samples t-test was used for normally distributed data (MDS-UPDRS III, 10MT-comfortable gait speed, and 10MT-fast gait speed). The Wilcoxon signed-rank test was used for non-normal data (axial subscores, bradykinesia subscores, tremor subscores, rigidity subscores, M-PAS, BBS, FTSTS, 6MWD, and TUG). aNormally distributed data are expressed as the mean ± SD, and bnon-normal data are reported as the median (interquartile range). *P < 0.05, **P < 0.01, vs. pre-MIRT. 10MT: 10-Meter Walk; 6MWD: 6-Minute Walk Distance; BBS: Berg Balance Scale; FTSTS: Five Times Sit to Stand; MDS-UPDRS III: Movement Disorder Society-Unified PD Rating Scales III; MIRT: multidisciplinary intensive rehabilitation treatment; M-PAS: Modified Parkinson Activity Scale; n: number of patients; PIGD: postural instability/gait difficulty; SD: standard deviation; TD: tremor dominant; TUG: Timed Get Up and Go.