(a) The mRNA level was significantly increased in NPC cells, especially in SNE-2 and 6-10B. (b,c) The transfection efficiency was determined by qRT-PCR. (d,e) Overexpression of Src-1 increased the cell viability of 6-10B. (e) Knockdown of Src-1 suppressed the cell viability of SNE-2. (f,g) Knockdown of Src-1 suppressed the cell viability of SNE-2. (h) EPIA analysis showed the expression of Src-1 and SP2 was in positive correlation. (i) SP2 was upregulation in NPC cells. **P < 0.01, ***P < 0.001 vs. NP69 or vector group.