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. 2021 Mar 2;14(2):e003304. doi: 10.1161/CIRCGEN.120.003304

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© 2021 The Authors.

Circulation: Genomic and Precision Medicine is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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Figure 2. — Cumulative incidence of coronary artery disease (CAD) in the subgroup of 40- to 54-y-old men in group III. Individuals are stratified by pooled cohort equations (PCE) and integrated risk tool (IRT)–defined risk (above/below the 7.5% threshold) into those predicted to be high risk by both PCE and IRT (red), those up-classified to high risk by IRT (purple), those down-classified to low risk by IRT (blue), and those predicted to be at low risk by both PCE and IRT (green).