FIG 4.

Gene expression of pvcrt and pvmdr1. Expression ratios (R) for pvcrt (A) and pvmdr1 (B) relative to the reference β-tubulin gene is displayed in log scale. Samples are stratified by treatment outcome and day of collection. Horizontal lines indicate medians and IQR. Dots indicate the type of recurrence based on identity-by-descent (IBD) analysis (black, IBD-homologous recurrence; gray, IBD-heterologous recurrence; white, undetermined by WGS). Adjusted P values from a pairwise Wilcoxon rank sum test with the Benjamini-Hochberg correction for multiple testing are reported. ACPR, adequate clinical and parasitological response; DRec, day of recurrence.