TABLE 4.

Number of TBF-resistant isolates showing different countries and mutations in the SQLE gene

Reference	Country	No. of all isolates	No. of resistant isolates	MIC (mg/liter)	Resistance rate (%)	Mutation(s)
10	Switzerland	412	1	3.2	0.24	Phe397Leu
36	India	64	39	1 to ≥32	60.94	Phe397Leu, Leu393Phe
2	India	63	20	4 to ≥32	31.75	Leu393Phe, Phe397Leu
5	India	129	105	1 to ≥32	81.40	Leu393Phe, Phe397Leu
37	Japan	24	1	2	4.17	None
24	India	146	15	≥2	10.27	Phe397Leu
16	India	498	102	1 to ≥32	20.50	Phe397Leu, Leu393Phe
19	India	279	202	0.25	72.00	Leu393Ser, Gln408Leu, His440Tyr, Ser443Pro, Leu335Phe, Ser395Pro
12	Iran	141	5	≥32	3.54	Phe397Leu, Leu393Ser