FIG 1.

Inflammasome gene expression in HFAs is induced by ZIKV, IFN-α, and poly(I·C). (A) Relative inflammasome gene expression in HFAs infected with ZIKV PRVABC-59 (MOI = 0.3) was determined by qRT-PCR at 48 h postinfection. (B) HFAs were treated with human recombinant IFN-α (rIFN-α) for 4, 8, and 12 h, after which relative NOD2 expression was determined. (C) HFAs were transfected with poly(I·C) for 12 h, after which relative inflammasome gene expression was determined. Error bars represent standard errors of the means. *, P < 0.05; **, P < 0.01; ***, P < 0.001 (by Student’s t test).