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Mutation analysis of the XDR and pan-CS variants. Heat map of unique, nonsynonymous mutations (single-nucleotide polymorphisms, insertions, and deletions) in (A) the six XDR variants and (B) the six pan-CS variants. Genes are organized by functional category. Mutations in intergenic regions (I) were only considered if the mutation fell within 100 bp upstream of the downstream gene’s start site. Intensity of color increases with mutation number.
