TABLE 4.
Case fatality and nephrotoxicity rates at different assessment points
| Treatment | No. (%) in study population |
Pa | ||
|---|---|---|---|---|
| Total (n = 542) | Combination therapy (n = 304) | Monotherapy (n = 238) | ||
| 7-day case fatality rate | 49 (9) | 18 (5.92) | 31 (13) | 0.007 |
| 30-day case fatality rate | 115 (21.2) | 48 (15.8) | 67 (28.1) | 0.001 |
| Persistent BSIb | 24 (4.4) | 7 (2.4) | 17 (7.20) | 0.014 |
| Incidence of nephrotoxicity at end of antibiotic treatment | 40 (7.4) | 18 (5.9) | 22 (9.2) | 0.2 |
a
Qualitative data were tested by the chi-square test.
b
BSI: bloodstream infection. Percentages are calculated based on the available data regarding persistent BSI (total study population, n = 533; monotherapy population, n = 236; combination therapy population, n = 297).