Table 3.

Correlation analysis between macrophage M1/M2 and hub genes in the training set and the validation set.

Cell marker	Gene	Training set		Validation set
		Correlation coefficient	P-value	Correlation coefficient	P-value
CD86	CA9	0.770	0.002	−0.030	0.935
	CCL14	0.167	0.586	−	-
	CCL20	0.429	0.143	−	-
	CXCL14	−0.032	0.917	−	-
	CXCL5	0.839	0	0.667	0.035
	GDF15	0.861	0	−0.397	0.046
	HMOX1	0.752	0.003	0.145	0.690
	IGFBP3	0.519	0.069	−	-
	SPP1	0.559	0.047	0.878	0.001
	VEGFA	0.997	0.000	−0.200	0.580
CD163	CA9	0.604	0.029	−0.217	0.546
	CCL14	0.279	0.355	−	-
	CCL20	0.654	0.015	−0.412	0.236
	CXCL14	0.011	0.973	−	-
	CXCL5	0.864	0	0.480	0.010
	GDF15	0.819	0.001	−0.591	0.072
	HMOX1	0.834	0	−0.222	0.008
	IGFBP3	0.585	0.036	0.501	0.097
	SPP1	0.715	0.006	0.852	0.002
	VEGFA	0.769	0.002	−0.579	0.008

CD86, cell marker of M1 macrophage; CD163, cell marker of M2 macrophage; Pearson test was used to perform correlation analysis.