Table 3. Severe perioperative complications and adverse events until intensive care unit discharge.

Procedure	Complication	Clavien Dindo
#11	Massive facial edema/mucosal bleeding requiring prolonged mechanical ventilation and oral tamponade	Grade IIIb
#22	Cervical hematoma and neck swelling requiring difficult airway management re-ETI and angiography intervention	Grade IVa
#26	Cervical hematoma and neck swelling requiring prolonged mechanical ventilation	Grade IIIb
#30	Massive facial edema requiring prolonged mechanical ventilation	Grade IIIb
#42	Excessive overinfusion leading to abdominal compartment syndrome and facial edema requiring 20 hours postoperative mechanical ventilation	Grade IIIb
#50	Renal failure requiring renal replacement therapy (CVVHDF)	Grade IVa
#51	Massive facial edema/mucosal bleeding and respiratory distress requiring difficult airway management re-ETI and oral tamponade	Grade IVa
#52	Massive groin hematoma due to dislocation of arterial introducer requiring premature termination of PHMP	Grade IIIa
#53	Neck swelling prior procedure during CVC placement requiring postponing of intervention and extubation	Grade IIIa

ETI, endotracheal intubation; CVVHDF, continuous veno-venous hemodiafiltration; PHMP, percutaneous hepatic melphalan perfusion; CVC, central venous catheter