Table 3.

Parameters associated with clinical long-term outcome.

Parameter	Univariate regression analysis (Significance)	Multivariable regression analysis† (Significance)
AST/ALT ratio	P = .01; OR = 1.23; CI = 1.05–1.44	Not significant
INR	P = .04; OR = 1.38; CI = 1.01–1.88	Not significant
IFNα-based therapy (yes vs no)	P = .04; OR = 0.29; CI = 0.89–0.94	Not significant
NA-therapy (yes vs no)	P = .01; OR = 4.92; CI = 1.51–16.01	Not significant
Liver cirrhosis (yes vs. no)	P = .001; OR = 7.44; CI = 2.16–25.62	Not significant
HBV DNA (yes vs no)	P = .05; OR = 0.30; CI = 0.09–0.99	Not significant
Albumin, g/dl	P = .04; OR = 0.04; CI = 0.00–0.34	P = .01; OR = 0.71; CI = 0.55–0.91
Platelets, 1000/nl	P = .002; OR = 0.98; CI = 0.97–0.99	P = .05; OR = 0.98; CI = 0.96–1.00

^†All parameters with P < .05 were considered for multivariable regression analysis. Nonsignificant parameters included in analysis were bilirubin, AST, ALT and gGT. ALT = alanine-aminotransferase, AST = aspartate-aminotransferase, CI = confidence interval, HBV = hepatitis B virus, IFNα = interferon alpha, INR = international normalized ratio, NA = nucleos(t)ide analogues, OR = odds ratio.