Table 1.
Timeline.
HIV-positive detection | ART for 16 days | ART for 26 days | 24 h After intestinal perforation | 48 Days after intestinal perforation | |
Diagnosis | Kaposi's sarcoma and AIDS | CMV Infection and IRIS | Intestinal perforation | Purulent peritonitis | Adhesive intestinal obstruction |
CD4+ cell count, cells/μL | 25 | 75 | No detection | No detection | No detection |
HIV RNA, copies/mL | No detection | 2.46 × 103 | No detection | No detection | No detection |
CMV DNA, copies/mL | 6.0 × 104 | 1.3 × 104 | No detection | No detection | <500 |
Symptoms | Purple blue nodules on the face and neck | Fever | Persistent left lower abdominal pain | Tenderness pain in the left upper abdomen and right lower abdomen and whole abdominal rebound pain and muscle tension. | Abdominal pain and vomiting |
ART | 3TC, TDF, nevirapine | 3TC, TDF, nevirapine | Discontinued ART | Discontinued ART | 3TC, TDF, nevirapine |
Treatment | Benzathine penicillin | Ganciclovir | Gastrointestinal decompression, proton pump inhibitors, ertapenem combined with levofloxacin, and nutritional support | Partial enterectomy and surgical repair of small bowel. Intravenous ganciclovir | Meropenem, rehydration transfusion, dopamine, gastrointestinal decompression |
ART = antiretroviral therapy, CMV = cytomegalovirus, IRIS = immune reconstitution inflammatory syndrome.