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. Author manuscript; available in PMC: 2021 Jul 16.
Published in final edited form as: Transplant Cell Ther. 2020 Sep 19;27(1):92.e1–92.e5. doi: 10.1016/j.bbmt.2020.09.017

Figure 1. CD39 deletion in lepr+ cells promoted allo-HSC engraftment.

Figure 1.

A. Allo-donor blood chimerism in Leprcre CD39fl/wt or control Leprcre mice. Recipient mice (B6) received 3-Gy irradiation followed by intravenous injection of MHC-mismatched BALB/c BM cells (2 × 107/each). Anti-CD8 mAb was intraperitoneally injected on day −1 and anti-mouse CD40L mAb on day 0. Donor chimerism frequencies in the peripheral blood 4 weeks after transplantation. Experiment included four-five recipients/group. Data were reproduced by an additional experiment (five mice/group).

B. Ratios of donor myeloid (CD11b+) to lymphoid (TCRβ+ and B220+) cells in the peripheral blood.