Table 6.
The pooled results of comparison between TAVR and SAVR for severe AS regarding to the 5-year outcomes.
| Pooled results | Heterogeneity | ||||||
| Subgroups | No. of study/pts | RR | 95% CI | P | I2 | Ph | Analytical effect model |
| TIA | 3/2967 | 1.50 | 1.04–2.17 | .03 | 0% | .88 | Fixed effects model |
| Major vascular complications | 1/699 | 2.95 | 1.64–5.32 | .0003 | |||
| Reintervention | 2/2268 | 3.40 | 1.47–7.85 | .004 | 0% | .86 | Fixed effects model |
| All-cause mortality | 4/3325 | 1.01 | 0.78–1.31 | .95 | 93% | <.00001 | Random-effect model |
| CV mortality | 4/3325 | 0.95 | 0.67–1.33 | .75 | 92% | <.00001 | Random-effect model |
| Stroke | 4/3325 | 1.13 | 0.93–1.36 | .22 | 0% | .70 | Fixed effects model |
| Rehospitalization | 3/3045 | 0.99 | 0.52–1.91 | .98 | 97% | <.00001 | Random-effect model |
| MI | 3/2967 | 1.20 | 0.90–1.58 | .21 | 49% | .14 | Fixed effects model |
| Endocarditis | 3/2967 | 1.40 | 0.89–2.20 | .14 | 0% | .64 | Fixed effects model |
| Permanent PM | 3/2967 | 1.94 | 0.85–4.40 | .11 | 90% | <.0001 | Random-effect model |
| Neurological events | 1/1988 | 1.24 | 1.00–1.53 | .05 | |||
AS = aortic stenosis, CI = confidence intervals, CV = cardiovascular, MI = myocardial infarction, RF = renal failure, RR = risk ratio, SAVR = surgical aortic valve replacement, TAVR = transcatheter aortic valve replacement, TIA = transient ischemic attacks.