Table 3.
Dynamic changes of blood cell count in patients with COVID-19.
| Laboratory parameters | time | All patients (n = 205) | Severe cases (n = 145) | Critical cases (recovered) (n = 29) | Critical cases (deaths) (n = 31) | χ2 value | P value |
| Leukocytes (×10E9/L; normal range 3.5–9.5) | 1 | 7.00 (5.10–9.45) | 6.80 (4.80–8.55) | 9.30 (7.05–12.90) | 8.40 (6.00–10.60) | 19.642 | ≦.001 |
| 2 | 7.10 (5.30–10.25) | 6.60 (5.15–8.95) | 8.90 (6.30–11.90) | 10.90 (5.80–16.20) | 17.109 | ≦.001 | |
| 3 | 6.80 (5.20–8.95) | 6.30 (5.10–7.65) | 7.30 (5.10–9.30) | 10.50 (8.40–18.30) | 30.108 | ≦.001 | |
| 4 | 6.50 (5.10–8.80) | 6.10 (4.90–7.50) | 7.10 (5.50–9.20) | 11.00 (8.10–17.90) | 32.078 | ≦.001 | |
| 5 | 6.40 (5.20–8.65) | 6.00 (5.00–7.55) | 6.30 (5.15–9.55) | 13.60 (7.70–24.70) | 42.167 | ≦.001 | |
| χ2 value | 5.926 | 6.617 | 13.062 | 8.012 | — | — | |
| P value | .205 | .158 | .011 | .091 | — | — | |
| Neutrophils (×10E9/L; normal range 1.8–6.3) | 1 | 4.33 (3.09–6.45) | 3.68 (2.80–4.80) | 8.05 (6.14–10.20) | 6.34 (5.27–9.86) | 61.805 | ≦.001 |
| 2 | 5.24 (3.47–8.28) | 4.32 (3.23–6.62) | 6.66 (4.84–10.14) | 9.34 (5.10–15.23) | 25.648 | ≦.001 | |
| 3 | 4.44 (3.38–7.04) | 4.02 (2.85–5.46) | 4.89 (3.71–7.05) | 9.18 (7.51–16.58) | 43.05 | ≦.001 | |
| 4 | 4.25 (2.95–6.13) | 3.61 (2.72–5.28) | 5.01 (3.41–6.51) | 9.82 (6.23–17.33) | 49.825 | ≦.001 | |
| 5 | 3.95 (3.00–6.37) | 3.68 (2.80–4.80) | 3.93 (3.06–6.35) | 11.24 (6.74–23.79) | 55.885 | ≦.001 | |
| χ2 value | 23.809 | 27.368 | 23.674 | 8.33 | — | — | |
| P value | ≦.001 | ≦.001 | ≦.001 | .08 | — | — | |
| Lymphocyte (×10E9/L; normal range 1.1–3.2) | 1 | 0.85 (0.55–1.22) | 0.97 (0.65–1.31) | 0.75 (0.48–1.12) | 0.57 (0.34–0.84) | 19.582 | ≦.001 |
| 2 | 0.14 (0.06–0.41) | 1.17 (0.76–1.60) | 0.97 (0.65–1.42) | 0.54 (0.34–0.92) | 64.19 | ≦.001 | |
| 3 | 1.17 (0.72–1.71) | 1.31 (0.90–1.83) | 1.13 (0.71–1.51) | 0.50 (0.38–0.71) | 3.465 | .063 | |
| 4 | 1.32 (0.82–1.76) | 1.47 (1.09–1.83) | 1.34 (0.95–1.76) | 0.49 (0.32–0.73) | 1.011 | .315 | |
| 5 | 1.44 (0.94–1.92) | 1.57 (1.14–1.97) | 1.46 (1.00–2.12) | 0.42 (0.27–0.84) | 41.14 | ≦.001 | |
| χ2 value | 9.33 | 26.53 | 7.578 | 3.998 | — | — | |
| P value | .002 | ≦.001 | .023 | .406 | — | — |
COVID-19 = coronavirus disease 2019; P values denoted the comparison between moderate and severe, critical and death cases. Data are shown as median (IQR); IQR = interquartile range; 1, 2, 3, 4, and 5: blood cell collection time point of admissions, 25%, 50%, 75% and discharge during their hospitalization.