Table 1.
Reference | Population (n) | Surgery | Control group | Study group | Outcomes |
Park et al (2019) | Control: n = 145 individualized PEEP: n = 147 | Elective pulmonary resection or esophagectomy | Protective ventilation group: PEEP 5 cm H2O | The driving pressure group: individualized PEEP | Postoperative complication, pneumonia or ARDS, in-hospital deaths, durations of intensive care unit stay, hospital stay, cerebral ischemic events, atrial fibrillation |
Ferrando et al (2014) | Control: n = 15 individualized PEEP: n = 15 | Elective lung resection | Control group: PEEP 5 cm H2O | Study group: individualized PEEP | Dynamic compliance, oxygenation during OLV, airway resistance, cardiac index |
Liu et al (2019) | PEEP5 group: n = 50 PEEPEIT group: n = 50 | Pneumonectomy, wedge resection, lobectomy, wedge + lobectomy | Control group: PEEP 5 cm H2O | Study group: individualized PEEP by EIT | pH, PCO2, PaO2/FiO2, Cdyn, Ppeak, Pmean, and Pplat during OLV, use of vasoactive drugs, lung complications, duration of hospitalization |
Mascott et al (2003) | Control: n = 22 individualized PEEP: n = 28 | Pneumonectomy, lobectomy, atypical lung resection | Control group: receive zero PEEP | Study group: individualized PEEP on the best thoracopulmonary compliance | Lung chest wall compliance, PaO2/FiO2, hypoxic events during OLV, postanesthesia care unit discharge |
Wu (2018) | Control: n = 28 individualized PEEP: n = 28 | Thoracoscopic lobectomy | control group: PEEP 5 cm H2O | Study group: individualized PEEP on the maximal static pulmonary compliance | Static pulmonary compliance, PaO2/FiO2 during OLV, Length of stay days of indwelling drainage tube, postoperative pulmonary complications |
Chen (2016) | Control: n = 39 individualized PEEP: n = 39 | Video-assisted right pulmonary lobectomy | Control group: PEEP 5 cm H2O | Study group: individualized PEEP | Dynamic compliance, arterial blood gas analysis during OLV |
Wen (2018) | Control: n = 33 individualized PEEP: n = 34 | Elective lobectomy | General lung protective ventilation group (P group): PEEP 5 cm H2O | Pulmonary ultrasound (L group): individualized PEEP by lung ultrasonography | Intraoperative hypoxic events, PaO2/FiO2 value during OLV, postoperative pulmonary complications, postoperative pain scores, cough, sputum, hospital stay |
Li et al (2020) | PCV + OLA group: n = 45 PCV group: n = 44 VCV + OLA group: n = 45 VCV group: n = 42 | Lobectomy wedge resection segmentectomy | PCV group: PEEP 5 cm H2O VCV group: PEEP 5 cm H2O | PCV + OLA group: PEEP produce the greatest dynamic compliance (Cdyn) VCV + OLA group: PEEP produce the greatest Cdyn | PaCO2, pH, PaO2/FiO2, plasma concentration of neutrophil elastase, postoperative pneumonia, atelectasis, acute respiratory failure, duration of intensive care unit stay, duration of hospital stay |
EIT = electrical impedance tomography, OLA = open-lung approach, OLV = one-lung ventilation, PCV = pressure-controlled ventilation, PEEP = positive end-expiratory pressure, VCV = volume-controlled ventilation.