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. 2021 Jul 16;100(28):e26638. doi: 10.1097/MD.0000000000026638

Table 1.

The characteristics of the included studies.

Reference Population (n) Surgery Control group Study group Outcomes
Park et al (2019) Control: n = 145 individualized PEEP: n = 147 Elective pulmonary resection or esophagectomy Protective ventilation group: PEEP 5 cm H2O The driving pressure group: individualized PEEP Postoperative complication, pneumonia or ARDS, in-hospital deaths, durations of intensive care unit stay, hospital stay, cerebral ischemic events, atrial fibrillation
Ferrando et al (2014) Control: n = 15 individualized PEEP: n = 15 Elective lung resection Control group: PEEP 5 cm H2O Study group: individualized PEEP Dynamic compliance, oxygenation during OLV, airway resistance, cardiac index
Liu et al (2019) PEEP5 group: n = 50 PEEPEIT group: n = 50 Pneumonectomy, wedge resection, lobectomy, wedge + lobectomy Control group: PEEP 5 cm H2O Study group: individualized PEEP by EIT pH, PCO2, PaO2/FiO2, Cdyn, Ppeak, Pmean, and Pplat during OLV, use of vasoactive drugs, lung complications, duration of hospitalization
Mascott et al (2003) Control: n = 22 individualized PEEP: n = 28 Pneumonectomy, lobectomy, atypical lung resection Control group: receive zero PEEP Study group: individualized PEEP on the best thoracopulmonary compliance Lung chest wall compliance, PaO2/FiO2, hypoxic events during OLV, postanesthesia care unit discharge
Wu (2018) Control: n = 28 individualized PEEP: n = 28 Thoracoscopic lobectomy control group: PEEP 5 cm H2O Study group: individualized PEEP on the maximal static pulmonary compliance Static pulmonary compliance, PaO2/FiO2 during OLV, Length of stay days of indwelling drainage tube, postoperative pulmonary complications
Chen (2016) Control: n = 39 individualized PEEP: n = 39 Video-assisted right pulmonary lobectomy Control group: PEEP 5 cm H2O Study group: individualized PEEP Dynamic compliance, arterial blood gas analysis during OLV
Wen (2018) Control: n = 33 individualized PEEP: n = 34 Elective lobectomy General lung protective ventilation group (P group): PEEP 5 cm H2O Pulmonary ultrasound (L group): individualized PEEP by lung ultrasonography Intraoperative hypoxic events, PaO2/FiO2 value during OLV, postoperative pulmonary complications, postoperative pain scores, cough, sputum, hospital stay
Li et al (2020) PCV + OLA group: n = 45 PCV group: n = 44 VCV + OLA group: n = 45 VCV group: n = 42 Lobectomy wedge resection segmentectomy PCV group: PEEP 5 cm H2O VCV group: PEEP 5 cm H2O PCV + OLA group: PEEP produce the greatest dynamic compliance (Cdyn) VCV + OLA group: PEEP produce the greatest Cdyn PaCO2, pH, PaO2/FiO2, plasma concentration of neutrophil elastase, postoperative pneumonia, atelectasis, acute respiratory failure, duration of intensive care unit stay, duration of hospital stay

EIT = electrical impedance tomography, OLA = open-lung approach, OLV = one-lung ventilation, PCV = pressure-controlled ventilation, PEEP = positive end-expiratory pressure, VCV = volume-controlled ventilation.