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. Author manuscript; available in PMC: 2023 Jan 1.
Published in final edited form as: Oral Dis. 2020 Dec 14;28(1):193–201. doi: 10.1111/odi.13746

Table 2.

Clinical Associations with ONJ

Clinical Variables Comparison vs Reference Odds Ratio 95% Confidence Interval P-Value Adjusted Odds Ratio 95% Confidence Interval P-Value
Race/Ethnicity Asian vs White 0.593 0.047–7.432 0.94
Black vs White 0.405 0.138–1.188 0.42
Other vs White 0.720 0.060–8.674 0.91
Osteoporosis Yes vs No 1.636 0.639–4.192 0.37
Tobacco History Yes vs No 1.195 0.482–2.965 0.70
Alcohol History Yes vs No 1.186 0.652–2.158 0.58
Dental Hygiene Moderate vs Good 0.718 0.288–1.792 0.46
Poor vs Good 1.070 0.357–3.209 0.68
Periodontal Disease History Yes vs No 0.575 0.253–1.307 0.19
Steroid Exposure Yes vs No 1.238 0.633–2.422 0.53
Bevacizumab Exposure Yes vs No 5.816 1.916–17.652 0.002 5.152 1.665–15.945 0.005
Bisphosphate agent Pamidronate vs Zoledronic Acid 0.244 0.074–0.799 0.04 0.181 0.033–0.974 0.047
Zoledronic & Pamidronate vs Zoledronic Acid 0.653 0.283–1.507 0.54 0.580 0.217–1.552 0.28
Time on Bisphosphonate Months (reported as β-coefficient) 0.995 0.982–1.007 0.49

Bold indicates statistically significant associations (p<0.05)