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Transcriptional regulation of AR-related gene expression. The cells were treated with compound I for 12 h, and the RNA was extracted. AR, PSA, and NKX3.1 gene expressions were examined with real time PCR (polymerase chain reaction). The results of T98G cells (A) and U87 cells (B) are shown with the quantification results. Data are expressed as mean ± SD (n = 3). *p < 0.05, **p < 0.01 compared to the DMSO treatment group by the unpaired t-test.
