Table 1.
Demographic and clinical signs of HFRS patients.
| Characteristics | Moderate (n = 13) | Severe (n = 10) | P-valuea |
|---|---|---|---|
| Demographic features | |||
| Male | 9 (69.2) | 10 (100.0) | 0.08 |
| Age, median years (IQR) | 45 (31–63) | 49 (30–60) | 0.86 |
| Occupation | Farmer (9), others (4) | Farmer (5), others (5) | 0.22 |
| Days post symptom debut, median (IQR) | 5 (4–6) | 4.5 (4–6) | 0.07 |
| Days of hospitalization, median (IQR) | 11 (9–12) | 17.5 (17–20) | <0.001 |
| Main lab finding on admissionb | |||
| APTT, median (IQR) | 40.7 (38.4–43.9) | 57.6 (53.8–62.3) | <0.001 |
| D-dimer, median (IQR) | 1.5 (0.8–2.1) | 3.7 (2.4–5.1) | 0.004 |
| MCHC, median (IQR) | 355 (350–357) | 367 (363–369) | 0.043 |
| NEUT counts× 109/L, median (IQR) | 5.0 (3.9–5.5) | 9.1 (4.3–16.9) | 0.046 |
| Platelet counts × 109/L, median (IQR) | 50.0 (33.0–65.0) | 15.5 (7.0–21.0) | 0.002 |
| WBC counts × 109/L, median (IQR) | 12.5 (11.1–14.8) | 20.4 (17.4–34.1) | 0.004 |
Abbreviations: IQR, interquartile range; APTT, activated partial thromboplastin time; HGB, determination of haemoglobin in blood; MCHC, mean corpuscular haemoglobin concentration; NEUT, neutrophil; WBC, white blood cell.
Kruskal–Wallis test or t-test. Significant P-values are shown in bold.
APTT: normal range, 22–38; D-dimer: normal range, 0–1; MCHC: normal range, 316–354 g/L; NEUT counts: normal range, 1.8–6.3 × 109/L; Platelet counts: normal range, 125–350 × 109/L; WBCs: normal range, 3.5–9.5 × 109/L. The normal ranges were referred to the National Health Commission of the People's Republic of China (WS/T 405-2012). Platelet counts and WBC counts were the maximum titres during hospitalization.