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Δ9-Tetrahydrocannabinol (THC) and cannabidiol (CBD) altered PPARα,γ associated pathways. PPARs are known to dimerize with RXR and their roles in metabolism are well established. Significant upregulation (FDR ≤ 0.05) of genes within this KEGG signaling pathway are highlighted in gradients of blue (THC), green (CBD), or both blue and green (both THC and CBD). Note that 1 gene in the data (FABP, logFC = −0.61, yellow) set was significantly downregulated for CBD.
