Table I.
Point of care (POC) devices used to produce autologous cell concentrate.
| Tissue sources | Withdrawal volume (ml) | Device name | Cell populations | Procedure | Cell characterization (Refs.) |
|---|---|---|---|---|---|
| Bone marrow | 60 | MarrowStim Zimmer Biomet | MNC, CD34+/MSC | Single use device kit to be centrifuged | Yes (170) |
| 240 | BMAC-Terumo | MNC, CD34+/MSC | Single use device kit to be centrifuged | Yes (171) | |
| Blood and bone marrow | 40-180 | Angel-Arthrex | cPRP | Automated system based on centrifugation and sensors technology | No |
| 120 | Sepax | MNC, TNC | Fully automated GMP compliant system for processing of umbilical cord blood, BM, PB. | Yes (172) | |
| Peripheral blood | 120 | Pall Celeris/MonoCells Athena/Hematrate Cook Regentec | MNC, TNC | Single use selective filter-based technology on cell membrane potential. No equipment needed. | Yes (65) |
| Adipose tissue | 100-130 | Lipogems | SVF micro-fragmented fat | Mechanical fragmentation through metal beads stainless steel marbles followed by centrifugation | Yes (58) |
| 25 | Adiprep TERUMO | Nucleated Cells and ASCs | Adipose cell concentrates from AT centrifugation | No | |
| 20 | HyTissue FIDIA | SVF micro-fragmented fat | Adipose cell fragmented concentrate from AT centrifugation after filtration | No |
MNCs, mononuclear cells; MSCs, mesenchymal cells; TNCs, total nuclear cells; cPRP, concentrate PRP from blood or blood/bone marrow; SVF, stromal vascular fraction; ASCs, adipose stem cells; AT, adipose tissue; BM, bone marrow.