Skip to main content
. Author manuscript; available in PMC: 2021 Jul 16.
Published in final edited form as: Science. 2021 Apr 2;372(6537):eabf3119. doi: 10.1126/science.abf3119

Fig. 8. Effect of entorhinal circuit perturbation on object-related firing.

Fig. 8.

(A to C) Two example single-cell responses each to cue and distractor objects for the first and last five trials of a control (A), MEC (B), and LEC (C) perturbation session. (D to F) Object DIs (see the materials and methods) were higher in the last five learning trials compared with the first five trials in control sessions [(D); P = 7.4 × 10−6, signed-rank test, n = 64 CA3-DG cells from 10 rats] and MEC perturbation sessions [(E); P = 2.1 × 10−3, n = 42 cells] but did not change during LEC perturbation [(F); P = 0.47, n = 47 cells]. MEC versus sham: P = 0.08, rank-sum test; LEC versus sham: P = 0.0014.